Details. Patients should induce vomiting or evacuate the stomach by lavage during Venofer overdoasge. Your doctor will do laboratory tests to monitor your response. This includes your doctors, nurses, pharmacists, and dentists. A very serious allergic reaction to this drug is unlikely, but get medical help right away if it occurs. Joint pain. Properly discard this product when it is expired or no longer needed. Theseside effectsmay last as long as they are undercancer treatment. Someside effectsare temporary or last as long as the person continues takingprescription medicine. <> Its important to note that youll get Injectafer doses from a doctor or healthcare professional in a medical facility. Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional. Weight changes may be due to symptoms of anemia improving. It may also cause nervousness, restlessness, and difficulty sleeping in some people. Venofer and the Venofer logo are registered trademarks of Vifor (International) Inc., Switzerland. People in the study received treatment with either Injectafer or Venofer. Injectafer and Feraheme can cause very similar side effects, but some different ones as well. Answer by DrLact: About Venofer usage in lactation. On day three I had a headache and felt heavy/exhausted, which lasted a few days. As with all medications, the cost of Injectafer can vary. Here we look at how Injectafer and Venofer are alike and different. I got Venofer twice in the last few years and now my iron deficiency is worse than ever, first time my hemoglobin is down to 11,2. Injectafer contains the active drug ferric carboxymaltose. But if they become more severe or dont go away, talk with your doctor or pharmacist. Throw away unused or expired drugs. This document does not contain all possible drug interactions. He said sometimes the reaction does show up after a few doses and unfortunately it takes longer to get over it. But keep in mind that in this study, delayed allergic reaction only occurred in one person. wAd**CgI%"nn{Oa[q{r5 Side effects from HRT depend on a number of factors: These lists contain up to 10 of the most common mild side effects that can occur with Injectafer, with Feraheme, or with both drugs (when taken individually). experience severe side effects, please seek medical attention right away and notify the ordering physician. Ask your doctor or healthcare provider if Venofer is the right choice for you. signs of inflammation in the lining of your stomach - pain or swelling, bloating, nausea, vomiting, loss of appetite, diarrhea, fever. <> Injectafer is approved to treat iron deficiency anemia (IDA). Is the ketogenic diet right for autoimmune conditions? However, be sure to take the dosage your doctor prescribes for you. endobj Brand-name medications usually cost more than generics. One class of immune checkpoint inhibitors targets the protein PD-1, which acts as a brake to keep the immune system in check. Your doctor will monitor your hemoglobin level to tell if Injectafer is working for you. Follow your doctor's directions carefully. Do not exceed 1,500 mg of iron per dosing course. Both of theseside effectscould worsen depression and lead tolife-threateningconsequences. Tell your doctor right away if you have any serious side effects, including: abdominal pain, chest pain, irregular heartbeat (arrhythmias), pressure in the chest, severe headache and blurred vision (hypertension), problems with your dialysis access site (graft). And this could lead to weight gain, if they increase their food intake. If you have more questions about how Injectafer will affect your anemia, talk with your doctor. Tell your doctor about the allergy and what signs you had. In clinical trials, serious allergic reactions occurred in 0.1% to 1.5% of people taking Injectafer. There may be drug take-back programs in your area. If this happens to you, your doctor may recommend that you receive another treatment course of Injectafer. This information should not be used to decide whether or not to take Venofer or any other medicine. Depending on your doctors instructions and Drug class: Iron products. Tell all of your health care providers that you take Venofer. There are different types of anemia, but IDA is the most common type. But some people have a delayed allergic reaction to certain drugs. Follow all instructions closely. fever. Below are examples of these side effects. "That's why it's so . This medication is given by injection into a vein as directed by your doctor. A boxed warning is the most serious warning the Food and Drug Administration (FDA) can issue about a drug. These lists contain up to 10 of the most common mild side effects that can occur with Injectafer, with Venofer, or with both drugs (when taken individually). (A class of medications describes a group of drugs that work in the same way.). Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect: All drugs may cause side effects. If you have symptoms of a low phosphorus level, call your doctor. Seriousside effectsshould be reported to a physician and/orPharmDfor medical advice. Other drugs are available that can treat iron deficiency anemia (IDA). Now I've just got mild nausea and have felt faint/dizzy a few times which is rare for me. And Feraheme is approved for use in adults who have CKD who may or may not need dialysis. Keep all drugs in a safe place. These changes could help improve your anemia on a long-term basis. Mild side effects of Injectafer can include:*. Generics tend to cost less than brand-name drugs. Serious side effects from Injectafer arent common, but they can occur. Heart failure: Could a low sodium diet sometimes do more harm than good? Iron is also necessary for your bone marrow to build healthy new red blood cells and provide oxygen to your . This is a sudden response affecting the entire body, which sometimes happens to people who are allergic to peanuts or beestings. Your doctor will be able to see how Venofer is working by reviewing your blood tests. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. This test measures the amount of hemoglobin in your blood. And if you dont have an allergic reaction to your first dose of a drug, its typically safe to assume you wont have an allergic reaction to doses that follow. Its not known whether its safe to breastfeed while youre taking Injectafer. Venofer can be given as a maximum of 200mg not more than 3 times per week; doses must be 24 hours apart. This is because alcohol reduces your bodys absorption of certain nutrients that are necessary to make red blood cells. Injectafer can be exposed to temperatures between 59F to 86F (15C to 30F) for a short period of time. Venofer is given as an infusion into a vein. Here are answers to some frequently asked questions about Injectafer. Infusion times range from less than 20 minutes to up to 4 hours. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. If you miss an appointment for your Injectafer dose, youll need to call your doctors office. Injectafer is indicated to treat iron deficiency anemia (IDA) in adults who meet one of the following criteria: Injectafer is administered intravenously, either by intravenous (IV) infusion or as an undiluted, slow IV push. For example, some people with anemia have extreme fatigue (lack of energy), which can make it hard for them to exercise. This is why they have a programcalledMedWatchthat encourages Americans to report adversereactions. In this group, after 35 days of treatment: In clinical studies, Injectafer was effective in treating IDA in adults with CKD who didnt require dialysis. Injectafer comes as a liquid solution inside vials. If you miss a dose, ask your doctor or pharmacist right away for a new dosing schedule. Those going through thismedical conditionshould speak to theircare teamfor support andguidance. You may report side effects to the FDA at 1-800-332-1088. Precautions. Note: The Food and Drug Administration (FDA) tracks side effects of drugs they have approved. If you have questions about drinking alcohol while youre taking Injectafer, talk with your doctor. 2. To help make sure that you dont miss appointments for your Injectafer doses, try setting an appointment reminder on your phone. This information is not specific medical advice and does not replace information you receive from the healthcare provider. Injectafer is approved to treat iron deficiency anemia (IDA) in certain adults with the condition. TheNational Instituteof Health (NIH) and the U.S.Food and Drug Administration(FDA) monitor the side effectsof new and approved medications to ensure safety. 3 0 obj Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat. Venofer is indicated to treat iron deficiency anemia (IDA) in adult and pediatric patients (2 years and older) with chronic kidney disease (CKD). Iron is important for many functions in the body, especially for the transport of oxygen in the blood. Muscle cramps, nausea, vomiting, strange taste in the mouth, diarrhea, constipation, headache, cough, back pain, joint pain, dizziness, or swelling of the arms/legs may occur. Venofer (iron sucrose) is given as an injection into the veins (intravenously or IV) by a trained healthcare provider. You may report side effects to FDA at 1-800-FDA-1088. Very bad and sometimes deadly allergic side effects have rarely happened. In this group, after 35 days of treatment: Effectiveness of Injectafer compared with a different IV iron product. Storage Condition Store in a cool and dry place protected from light. Sharing this information can help you avoid potential interactions. Additional studies are ongoing to see if Injectafer is a safe and effective treatment option for these conditions. Its possible that after getting two doses of Injectafer, your anemia may go away completely. Injectafer isnt available in a generic form. One study of just under 5000 HRT users found that 43% were affected. I actually was constipated after my 3rd but didn't think anything of it. If you come into contact with Red Tide, it can cause respiratory irritation, coughing, and sneezing. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Common MRI side effects include dizziness, anxiety, headache, nausea, hearing loud noises, and feeling chilled or hot in the MRI scanner. Or your doctor may recommend that you change your eating habits to include more iron in your diet. Which tests can diagnose iron deficiency anemia? With IDA, you have low hemoglobin levels. upper respiratory infection. But so far I feel better than before the infusion. For example: Say you weigh 105 pounds (about 48 kilograms). If youre not sure if youll need to get prior authorization for Injectafer, contact your insurance company. If you have a severe allergic reaction to Injectafer after youve left the medical facility where you received your dose of the drug, call your doctor right away. Feraheme is also approved to treat IDA in adults who either didnt have improvement in their IDA or had side effects with iron treatment thats taken by mouth. If you have questions about side effects, call your doctor. Grapefruitjuice may be healthy for people to drink, but it can cause someseriousside effects. So you wont pick up this medication from a pharmacy. Do not exceed 1,500 mg of iron per dosing course. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. cough. Call your doctor right away if you have chest pain, cough or the need to cough, dizziness, passing out, shortness of breath, sweating, or throat tightness. Last updated on Feb 20, 2023. Administer Venofer in 3 divided doses, given by slow intravenous infusion, within a 28 day period: 2 infusions each of 300 mg over 1.5 hours 14 days apart followed by one 400 mg infusion over 2.5 hours 14 days later. The information provided is not intended to replace your healthcare provider's medical advice. Iron is a vital mineral in the body, central to transporting oxygen around the body in the hemoglobin. If you have questions about the safety of breastfeeding while youre taking Injectafer, talk with your doctor. This medicine is sometimes given slowly, and the infusion can take up to 2.5 hours to complete. Hypophosphatemia has been reported in people using Injectafer after the drug was released onto the market. And babies born to those who took Injectafer during pregnancy didnt have any major congenital anomalies (also sometimes called birth defects). Youll receive doses of either drug by a healthcare professional at a medical facility. Otherwise, call a poison control center right away. This allows them to manage any side effects that you may have following your dose. Others last much longer (even a lifetime), which can be quite traumatizing to people. Call your healthcare provider or get medical help right away if you have symptoms of an allergic reaction, including but not limited to rash, chest pain, cough, dizziness, passing out, shortness of breath, sweating or throat tightness. People who weigh 110 pounds (about 50 kilograms) or more will receive two separate Injectafer doses of 750 milligrams each. Most people will metabolize medication by half every time it circulates the body.