People Over 100 Have Good DNA

[ad_1]

June 2, 2021 — We can learn a lot from our elders, not just from their experience, but also from their genes, say Italian scientists who, for the first time, have decoded the DNA of people older than 100 to figure out how they avoided age-related diseases.

“The 105 threshold is really tough to jump and those who surpass it are really super athletes in terms of aging,” according to Paolo Garagnani, PhD, associate professor of general pathology at the University of Bologna.

These “super centenarians” are remarkable because they also tend to avoid the long periods of illness that so often overshadow the last few years of an older person’s life, he says.

To find out what separates the oldest of the old from the average person, Garagnani and his team scoured Italy for people who had reached 105 and sequenced their genomes to determine how they had been able to live so long.

Italy is ideal for research like this because its population has one of the longest life expectancies in the world and the Catholic Church in the region keeps precise records of baptisms, which assists researchers in verifying people’s ages.

The scientists took blood samples from 81 people and conducted whole-genome sequencing to look for differences between the centenarians and younger people. And they found that people who live past 100 tend to have a unique genetic background that makes their bodies very efficient at repairing DNA.

The scientists also identified five common genetic changes between two genes, the COA1 and STK17A. These genes are involved in areas important to the health of human cells and the development of cancer, heart attack, and stroke, which are diseases that centenarians seem to be at a lower risk for, Garagnani says.

Most of the people the scientists met with were living independently past the age of 100 and weren’t held back by illness. Often people who live this long, he explains, tend to die suddenly. “When enough is enough for them, they go in a couple of days or a week.”



WebMD Health News


Sources

Paolo Garagnani, PhD, associate professor of general pathology, University of Bologna, Italy.


eLife: “Whole-genome sequencing analysis of semi-supercentenarians.”



© 2021 WebMD, LLC. All rights reserved.



[ad_2]

Source link

80 thoughts on “People Over 100 Have Good DNA

  • September 16, 2023 at 3:44 pm
    Permalink

    Remarkable! Its actually awesome piece of writing, I have got much clear idea regarding from this post.

  • September 18, 2023 at 4:10 pm
    Permalink

    Hi, I do think this is an excellent website. I stumbledupon it
    😉 I may revisit once again since I book-marked it. Money and
    freedom is the greatest way to change, may you be rich
    and continue to help others.

  • September 18, 2023 at 4:15 pm
    Permalink

    Thanks a bunch for sharing this with all folks you actually realize what you’re speaking about!
    Bookmarked. Please additionally discuss with my site =).
    We can have a link trade agreement between us

  • September 18, 2023 at 4:24 pm
    Permalink

    If some one needs expert view about blogging after that i recommend him/her
    to go to see this website, Keep up the nice work.

  • September 18, 2023 at 4:40 pm
    Permalink

    Way cool! Some extremely valid points! I appreciate you writing this post and the rest of
    the website is extremely good.

  • September 18, 2023 at 4:44 pm
    Permalink

    This paragraph will help the internet viewers for creating
    new web site or even a blog from start to end.

  • September 18, 2023 at 4:44 pm
    Permalink

    Hello! This is my first visit to your blog!

    We are a group of volunteers and starting a new project in a community in the same niche.
    Your blog provided us beneficial information to work
    on. You have done a outstanding job!

  • September 18, 2023 at 4:47 pm
    Permalink

    Great article. I am experiencing some of these issues as well..

  • September 18, 2023 at 5:00 pm
    Permalink

    I’m extremely impressed with your writing skills as well as with
    the layout on your weblog. Is this a paid theme or did you customize it yourself?

    Either way keep up the nice quality writing,
    it is rare to see a nice blog like this one today.

  • September 18, 2023 at 8:02 pm
    Permalink

    Having read this I believed it was really informative.
    I appreciate you spending some time and effort to put this information together.
    I once again find myself personally spending a significant amount of
    time both reading and commenting. But so what, it was still worthwhile!

  • September 18, 2023 at 8:05 pm
    Permalink

    Hurrah! In the end I got a web site from where I be able
    to truly take useful facts regarding my study and knowledge.

  • September 18, 2023 at 8:06 pm
    Permalink

    Very energetic post, I enjoyed that bit. Will there be a
    part 2?

  • September 18, 2023 at 8:19 pm
    Permalink

    Heya i’m for the first time here. I found this board and I find
    It truly useful & it helped me out a lot. I hope to give something back and aid others like you helped me.

  • September 18, 2023 at 8:26 pm
    Permalink

    I am regular visitor, how are you everybody?
    This post posted at this web page is in fact pleasant.

  • September 18, 2023 at 8:30 pm
    Permalink

    Good post. I learn something totally new and challenging on blogs I stumbleupon on a daily basis.
    It will always be helpful to read through articles from other authors and use a
    little something from their websites.

  • September 18, 2023 at 8:35 pm
    Permalink

    I pay a quick visit daily some sites and blogs to read articles,
    but this blog provides feature based writing.

  • September 18, 2023 at 8:35 pm
    Permalink

    A fascinating discussion is worth comment.
    There’s no doubt that that you should publish more about this topic, it may not be a taboo subject but
    typically folks don’t speak about these subjects.
    To the next! Cheers!!

  • September 18, 2023 at 8:42 pm
    Permalink

    Hey there! Someone in my Facebook group shared this site with us
    so I came to look it over. I’m definitely loving the information. I’m bookmarking and
    will be tweeting this to my followers! Fantastic blog and
    fantastic style and design.

  • September 18, 2023 at 8:47 pm
    Permalink

    I am not sure where you’re getting your info, but good topic.
    I needs to spend some time learning much more or understanding more.
    Thanks for great information I was looking for this information for my mission.

  • September 18, 2023 at 9:05 pm
    Permalink

    Hello just wanted to give you a quick heads up.
    The words in your article seem to be running off the screen in Chrome.

    I’m not sure if this is a formatting issue or something to do with
    browser compatibility but I thought I’d post to let you know.
    The style and design look great though! Hope you get the problem fixed soon. Many thanks

  • September 19, 2023 at 2:09 pm
    Permalink

    What’s Happening i am new to this, I stumbled upon this I’ve discovered It positively
    helpful and it has helped me out loads. I hope to give a contribution & assist other users like its helped
    me. Good job.

  • September 26, 2023 at 3:00 am
    Permalink

    Thank you for some other informative web site. Where else could I am getting that
    type of info written in such a perfect approach? I have a challenge that I’m simply
    now running on, and I have been at the look out for such info.

  • September 26, 2023 at 7:27 am
    Permalink

    Excellent site. A lot of useful info here.
    I am sending it to several buddies ans additionally sharing
    in delicious. And certainly, thank you for your effort!

  • September 26, 2023 at 8:18 am
    Permalink

    You are so cool! I do not think I have read anything like this before.
    So nice to find another person with a few genuine thoughts on this topic.
    Really.. thank you for starting this up. This site
    is one thing that is needed on the internet, someone with
    a little originality!

  • September 26, 2023 at 9:17 am
    Permalink

    My spouse and I stumbled over here coming from a different page and thought
    I may as well check things out. I like what I see so i am just following you.
    Look forward to exploring your web page for a second
    time.

  • September 26, 2023 at 9:49 am
    Permalink

    I enjoy reading an article that will make people think.
    Also, many thanks for allowing for me to comment!

  • September 26, 2023 at 11:42 am
    Permalink

    This excellent website definitely has all the
    info I wanted about this subject and didn’t know who to ask.

  • September 26, 2023 at 2:29 pm
    Permalink

    As the admin of this web page is working, no hesitation very rapidly it
    will be famous, due to its quality contents.

  • September 26, 2023 at 7:45 pm
    Permalink

    I know this if off topic but I’m looking into starting my own weblog and was curious what all is required
    to get set up? I’m assuming having a blog like yours
    would cost a pretty penny? I’m not very web smart so I’m not 100% certain. Any recommendations or advice would be greatly appreciated.

    Thank you

  • September 27, 2023 at 5:53 am
    Permalink

    Thank you for the auspicious writeup. It in fact was a amusement account it.
    Look advanced to far added agreeable from you! However, how can we communicate?

  • September 27, 2023 at 6:36 am
    Permalink

    This is my first time pay a visit at here and i am in fact pleassant to read all
    at alone place.

  • September 27, 2023 at 7:00 am
    Permalink

    Thanks for the marvelous posting! I certainly enjoyed
    reading it, you will be a great author.I will be sure to
    bookmark your blog and will often come back in the foreseeable future.
    I want to encourage continue your great posts, have a nice morning!

  • September 27, 2023 at 7:43 am
    Permalink

    Hi there! I’m at work browsing your blog from my new iphone 3gs!

    Just wanted to say I love reading through your blog
    and look forward to all your posts! Carry on the superb work!

  • October 2, 2023 at 3:35 pm
    Permalink

    Hello friends, nice piece of writing and nice arguments commented here, I am genuinely enjoying
    by these.

  • October 4, 2023 at 7:56 pm
    Permalink

    For instance, some lenders will not approve loans for educational expenditures.

  • October 6, 2023 at 1:32 am
    Permalink

    Pretty component to content. I just stumbled upon your web site and in accession capital to say that I
    acquire in fact loved account your weblog posts. Anyway
    I’ll be subscribing in your feeds or even I achievement you
    get right of entry to constantly quickly.

  • October 6, 2023 at 1:34 am
    Permalink

    Hello! Do you know if they make any plugins to protect against hackers?
    I’m kinda paranoid about losing everything I’ve worked hard on. Any suggestions?

  • October 6, 2023 at 1:44 am
    Permalink

    I’m extremely impressed with your writing skills and also with the layout on your blog.
    Is this a paid theme or did you customize it yourself?
    Anyway keep up the excellent quality writing, it
    is rare to see a nice blog like this one these days.

  • October 6, 2023 at 1:46 am
    Permalink

    Hi there, yes this article is in fact pleasant and I have
    learned lot of things from it about blogging.
    thanks.

  • October 6, 2023 at 1:47 am
    Permalink

    Everyone loves what you guys are usually up too. This type of clever work and coverage!
    Keep up the great works guys I’ve included you guys to
    blogroll.

  • October 6, 2023 at 1:50 am
    Permalink

    Hey there! This post could not be written any better!
    Reading this post reminds me of my previous room mate!

    He always kept chatting about this. I will forward
    this post to him. Fairly certain he will have a good read.
    Many thanks for sharing!

  • October 6, 2023 at 1:54 am
    Permalink

    I am truly pleased to read this web site posts which includes
    plenty of helpful data, thanks for providing these
    information.

  • October 6, 2023 at 2:05 am
    Permalink

    If some one desires to be updated with newest technologies therefore he must be
    pay a visit this site and be up to date everyday.

  • October 6, 2023 at 2:07 am
    Permalink

    What’s up, I would like to subscribe for this website
    to get most recent updates, thus where can i do
    it please help out.

  • October 6, 2023 at 2:13 am
    Permalink

    First off I want to say wonderful blog! I had a quick question that I’d
    like to ask if you don’t mind. I was interested to know
    how you center yourself and clear your head before writing.
    I have had trouble clearing my thoughts
    in getting my ideas out there. I truly do enjoy writing but it just seems like the
    first 10 to 15 minutes are usually lost just trying to figure out how to begin.
    Any suggestions or tips? Appreciate it!

  • October 6, 2023 at 2:27 am
    Permalink

    Thank you for another excellent post. Where else could anyone get that kind of info in such a perfect manner of writing?
    I have a presentation subsequent week, and I’m at the look for
    such info.

  • October 6, 2023 at 2:31 am
    Permalink

    Hi, Neat post. There’s an issue together with your
    web site in web explorer, could check this? IE still is the marketplace
    chief and a big section of people will pass over your great writing due to
    this problem.

  • October 6, 2023 at 4:55 pm
    Permalink

    Cool blog! Is your theme custom made or did you download it from somewhere?
    A design like yours with a few simple adjustements would really make my blog stand out.
    Please let me know where you got your theme. Bless you

  • October 6, 2023 at 9:43 pm
    Permalink

    Everything is very open with a really clear explanation of the challenges.
    It was truly informative. Your website is extremely helpful.
    Thank you for sharing!

  • October 6, 2023 at 9:54 pm
    Permalink

    Hello, I check your blog regularly. Your humoristic style is awesome, keep doing what you’re doing!

  • October 8, 2023 at 7:54 am
    Permalink

    For instance, if you have an FHA, VA, or USDA loan, the upfront mortgage insurance premium or
    funding fee will seem in this section.

  • October 9, 2023 at 9:55 pm
    Permalink

    Attractive portion of content. I just stumbled upon your web site and in accession capital to claim that I acquire in fact enjoyed
    account your weblog posts. Any way I’ll be subscribing in your
    feeds or even I achievement you access constantly fast.

  • October 10, 2023 at 2:39 pm
    Permalink

    Howdy outstanding website! Does running a blog similar to this take a lot of work?
    I’ve virtually no understanding of programming however I had
    been hoping to start my own blog in the near future.

    Anyways, should you have any recommendations or techniques for new blog owners please share.
    I understand this is off subject nevertheless I just had to ask.
    Cheers!

  • October 10, 2023 at 2:40 pm
    Permalink

    Yesterday, while I was at work, my sister stole my iphone and tested
    to see if it can survive a 25 foot drop, just so she can be a youtube sensation. My apple ipad is now destroyed and she has 83 views.
    I know this is completely off topic but I had to share it with someone!

  • October 10, 2023 at 2:40 pm
    Permalink

    I know this web site presents quality dependent articles or
    reviews and other material, is there any other
    site which offers these kinds of information in quality?

  • October 10, 2023 at 2:41 pm
    Permalink

    Howdy just wanted to give you a quick heads up and let you know a few of the images aren’t loading properly.

    I’m not sure why but I think its a linking issue. I’ve tried it in two different web browsers and
    both show the same results.

  • October 10, 2023 at 2:42 pm
    Permalink

    Hello there! This post couldn’t be written any better! Reading this post reminds me of my
    good old room mate! He always kept chatting about this.
    I will forward this page to him. Pretty sure he will have a good read.
    Many thanks for sharing!

  • October 10, 2023 at 2:43 pm
    Permalink

    Wow! Finally I got a weblog from where I be capable of truly take valuable data
    regarding my study and knowledge.

  • October 10, 2023 at 2:44 pm
    Permalink

    Incredible! This blog looks just like my old one! It’s on a completely different topic but it has pretty much the same page layout and design. Great choice of colors!

  • October 10, 2023 at 2:45 pm
    Permalink

    I am extremely impressed with your writing talents as smartly
    as with the structure on your blog. Is this a paid subject or did you modify it
    your self? Anyway stay up the excellent quality writing,
    it’s rare to see a nice weblog like this one these days..

  • October 10, 2023 at 2:45 pm
    Permalink

    If you want to improve your know-how simply keep visiting this web site and be updated with the hottest information posted here.

  • October 10, 2023 at 2:46 pm
    Permalink

    Excellent blog here! Also your site loads up very fast! What
    web host are you using? Can I get your affiliate link to your host?
    I wish my website loaded up as quickly as yours
    lol

  • October 10, 2023 at 2:48 pm
    Permalink

    I am sure this article has touched all the internet people, its really really
    pleasant article on building up new weblog.

  • October 10, 2023 at 2:49 pm
    Permalink

    I constantly spent my half an hour to read this webpage’s articles daily along with a cup of coffee.

  • October 10, 2023 at 2:50 pm
    Permalink

    If you want to take a good deal from this post then you have to apply these methods to your won webpage.

  • October 10, 2023 at 2:51 pm
    Permalink

    Excellent article. I am experiencing many of these issues
    as well..

  • October 14, 2023 at 8:30 am
    Permalink

    What’s up, all is going nicely here and ofcourse every one is sharing
    data, that’s actually excellent, keep up writing.

  • October 14, 2023 at 8:33 am
    Permalink

    Greetings! I know this is somewhat off topic but
    I was wondering if you knew where I could find a captcha plugin for my comment form?
    I’m using the same blog platform as yours and I’m having problems finding
    one? Thanks a lot!

  • October 14, 2023 at 8:46 am
    Permalink

    Does your blog have a contact page? I’m having trouble
    locating it but, I’d like to send you an e-mail.
    I’ve got some ideas for your blog you might be
    interested in hearing. Either way, great website
    and I look forward to seeing it improve over time.

  • October 14, 2023 at 8:47 am
    Permalink

    Hey there! This is my first comment here so I just wanted to give a quick shout out and tell you I really enjoy reading your blog posts.
    Can you recommend any other blogs/websites/forums that go over the
    same subjects? Thanks for your time!

  • October 14, 2023 at 8:49 am
    Permalink

    If some one wants to be updated with newest technologies afterward he must be
    visit this web page and be up to date daily.

  • October 14, 2023 at 7:48 pm
    Permalink

    Cafe Casino has a fantastic buyer service group offered 24/7 to help you.

  • October 20, 2023 at 9:17 am
    Permalink

    Ridiculous quest there. What occurred after? Thanks!

  • October 20, 2023 at 7:38 pm
    Permalink

    Hi friends, its fantastic post regarding teachingand completely explained, keep it up
    all the time.

  • October 20, 2023 at 7:46 pm
    Permalink

    Great goods from you, man. I’ve understand your stuff
    previous to and you are just too fantastic. I really like what you’ve acquired
    here, certainly like what you’re stating and the way in which you say it.

    You make it entertaining and you still care for to keep it sensible.
    I can not wait to read far more from you. This is really a tremendous web site.

Leave a Reply

Your email address will not be published.